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*JOIN THE PHYSIONIC INSIDERS [PREMIUM CONTENT]* Join the Physionic Insiders: https://bit.ly/PhysionicInsiders2 *HEALTH AUTONOMY [COURSE]* Learn to Analyze & Apply Studies for Yourself: https://bit.ly/healthautonomy *JOIN THE COMMUNITY* Join my Community [It’s Free!]: https://bit.ly/PhysionicCommunity2 *EMAIL LIST* 1-2 Weekly Email of Value [It’s Free!]: http://bit.ly/2AXIzK6 *HIRE ME FOR CONSULTING:* Consulting: https://bit.ly/3dmUl2H 0:00 - Introduction 1:26 - Cochrane Analysis Background - Were we Wrong? 4:08 - Biases in Blood Pressure Studies 6:51 - Relative vs Absolute Risk - Knowing the Difference 10:48 - Risks with Lower Blood Pressure 16:41 - Were we all wrong? 26:45 - Main Points Dr. Boz's Video: https://www.youtube.com/live/iddnc_tR-T0?si=MLZNlzDxaNk5Qxpz References [Study 413] SPRINT Research Group, Wright JT Jr, Williamson JD, et al. A Randomized Trial of Intensive versus Standard Blood-Pressure Control [published correction appears in N Engl J Med. 2017 Dec 21;377(25):2506. doi: 10.1056/NEJMx170008.]. N Engl J Med. 2015;373(22):2103-2116. doi:10.1056/NEJMoa1511939 Funding/Conflicts: Public Funding [National Institutes of Health (NIH); Clinical and Translational Science Awards; Department of Veterans Affairs] // Potential Conflicts of Interest [Drugs were donated by Takeda and Arbor Pharmaceutical] [Study 437] Saiz LC, Gorricho J, Garjón J, Celaya MC, Erviti J, Leache L. Blood pressure targets for the treatment of people with hypertension and cardiovascular disease. Cochrane Database Syst Rev. 2022;11(11):CD010315. Published 2022 Nov 18. doi:10.1002/14651858.CD010315.pub5 Funding/Conflicts: Public Funding [This project was supported by the [Cochrane Hypertension Group] through infrastructure funding from the [National Institute for Health Research (NIHR)] // No direct Conflicts of Interest [C] ACCORD Study Group, Cushman WC, Evans GW, et al. Effects of intensive blood-pressure control in type 2 diabetes mellitus. N Engl J Med. 2010;362(17):1575-1585. doi:10.1056/NEJMoa1001286 [D] Yang Q, Zheng R, Wang S, et al. Systolic Blood Pressure Control Targets to Prevent Major Cardiovascular Events and Death in Patients With Type 2 Diabetes: A Systematic Review and Network Meta-Analysis. Hypertension. 2023;80(8):1640-1653. doi:10.1161/HYPERTENSIONAHA.123.20954 ********CRITIQUES, RULES, AND NOTES******** Be aware of the following rules before posting comments: - Please do not post summaries of the video in the comments - it damages retention on the video and YouTube is less likely to promote it (these videos cost me a lot of money to produce). Critiques of my work are welcome! Please be aware of the following notes & rules before submitting critique: Be mindful that this content is not all encompassing on the subject at hand and is self-limited for brevity to reach a wider audience. Also, be aware that I receive hundreds of YouTube comments per day, so the only way your critique can be considered is if you follow the steps outlined below. Finally, YouTube auto-deletes links, so I do not see most comments with links attached. RULES: If your comment is rude, you will be banned. If your comment is not about the studies/topics at hand (i.e. extending to other outcomes not discussed) or offers critique with no scientific basis, it is unlikely to receive a response. If you can follow these rules, I will try to address your critique and if there is merit, I will add an AMENDMENT to the content in question and pin it so everyone can see it (thank you!). Please use the following link to submit your critique: https://bit.ly/PhysionicCritique Disclaimer: None of the information provided by this brand is a replacement for your physician's advice. This brand is information for the sake of knowledge and the options of choice it provides, not in any way a personalized prescription. Please consult your physician before making any health related changes.