Is Lifting Weights the Best Dementia Prevention? Muscle’s Impact on Brain Health | Dr. Perlmutter

DavidPerlmutterMD February 10, 2025
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David Perlmutter, MD, FACN, ABIHM is a board-certified neurologist. He serves on the Scientific Advisory Board of the American Nutrition Association and is a Fellow of the American College of Nutrition. Dr. Perlmutter received his M.D. degree from the University of Miami School of Medicine. After completing residency training in neurology, also at UMiami, Dr. Perlmutter entered private practice. Dr. Perlmutter is the recipient of the Linus Pauling Award, the Humanitarian of the Year Award from the American College of Nutrition, and the 2019 Global Leadership Award from the Integrative Healthcare Symposium. Dr. Perlmutter's books include the #1 New York Times bestseller Grain Brain. Other New York Times bestsellers include Brain Maker, The Grain Brain Cookbook, The Grain Brain Whole Life Plan, and Brain Wash, co-written w/ Austin Perlmutter, MD. His latest book, Drop Acid, focuses on the pivotal role of uric acid in metabolic diseases and will be published in February 2022.

Video Description

🧠 Stay ahead with the latest in science, nutrition, and wellness by subscribing to Dr. Perlmutter’s newsletter at: www.drperlmutter.com. ✉️🌱 We all know that exercise is good for the body and specifically, very good for the brain. In fact, exercise is the most important inroad to better brain health, better brain function, protecting the brain against decline, and even with respect to mood issues like depression. But it's reasonable to ask how in fact does this work? How is it that exercising muscles does good things for the brain? On today's episode of the Empowering Neurologist we spent time with Dr. Austin Perlmutter. He takes us on a deep dive exploring the exact connection between muscle and its endocrine function in terms of creating various chemicals that are so helpful for better brain health. It's a great discussion that looks at things like how much exercise is appropriate, what type of exercise is best, how much protein we should be consuming, and what other supplements will augment the benefits of exercise in terms of better brain health. I think you will really enjoy this episode. I know I sure did, after all, getting to spend time with my son is always special! ===== 00:00:00 Introduction & Welcoming Dr. Austin 00:01:56 The Relationship of Muscle Health, Mental Health, and Brain Health 00:09:15 The Power of Exercise to Improve Cognition vs Pharmaceuticals & The Muscle as an Endocrine Organ 00:16:36 The Molecules Produced by Muscles: Myokines 00:20:10 Myokines, Inflammation, and Metabolic Health 00:26:43 Sarcopenia and The Risk of Dementia 00:31:50 Brain Derived Neurotropic Factor, Neuroplasticity & Weight Training 00:39:40 Animal versus Plant Protein to Build Healthy Muscle 00:46:26 Cycling Anabolic and Catabolic States 00:51:31 Why Women Are 2x More Likely to Develop Alzheimer's and What Supplementation Is Necessary to Compliment Building Muscle 01:05:40 Conclusion and Wrap Up ===== Dr. Austin Perlmutter is a board-certified internal medicine physician, New York Times bestselling author, researcher, educator, podcaster and entrepreneur. His mission is to help people get their brains unstuck for better mental and cognitive health. Dr. Perlmutter’s work on how environment and diet influences brain health has been featured on PBS, Rolling Stone, Newsweek, NPR, Fox, CBS and other top media outlets. He has co-produced and hosted some of the world’s largest online brain health events including Alzheimer’s, the Science of Prevention and the Better Brain Blueprint. He is the Managing Director of Big Bold Health, where he led a pioneering study exploring plant nutrient effects on human aging. He is the CEO of Lichen Air, which provides science-backed indoor air solutions for better brain health and longevity. He is also a research consultant to the Helfgott Research Institute, where he studies the epigenetic, metabolic, microbiome and immune effects of ayahuasca. Website: https://www.austinperlmutter.com/ YouTube: https://www.youtube.com/@draustinperlmutter IG: https: https://www.instagram.com/draustinperlmutter/ Lichen AIr: https://lichenair.com/ Dr. Austin Perlmutter's Muscle-Brain eGuide: https://www.austinperlmutter.com/muscleguide ___________________________ Instagram: https://www.instagram.com/davidperlmutter/ Website: https://www.drperlmutter.com/ Subscribe to our channel: https://www.youtube.com/channel/UCDRl_UAXxbHyOOjklnA0dxQ/?sub_confirmation=1

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