State-Of-The-Art Prompting For AI Agents

Y Combinator June 24, 2025
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At first, prompting seemed to be a temporary workaround for getting the most out of large language models. But over time, it's become critical to the way we interact with AI. On the Lightcone, Garry, Harj, Diana, and Jared break down what they've learned from working with hundreds of founders building with LLMs: why prompting still matters, where it breaks down, and how teams are making it more reliable in production. They share real examples of prompts that failed, how companies are testing for quality, and what the best teams are doing to make LLM outputs useful and predictable. The prompt from Parahelp (S24) discussed in the episode: https://parahelp.com/blog/prompt-design Apply to Y Combinator: https://ycombinator.com/apply Work at a startup: https://workatastartup.com Chapters (Powered by https://chapterme.co/) - 0:00 Intro 0:58 Parahelp’s prompt example 4:59 Different types of prompts 6:51 Metaprompting 7:58 Using examples 12:10 Some tricks for longer prompts 14:18 Findings on evals 17:25 Every founder has become a forward deployed engineer (FDE) 23:18 Vertical AI agents are closing big deals with the FDE model 26:13 The personalities of the different LLMs 27:26 Lessons from rubrics 29:47 Kaizen and the art of communication 31:00 Outro