The Quest to ‘Solve All Diseases’ with AI: Isomorphic Labs’ Max Jaderberg
Sequoia Capital
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Video Description
After pioneering reinforcement learning breakthroughs at DeepMind with Capture the Flag and AlphaStar, Max Jaderberg aims to revolutionize drug discovery with AI as Chief AI Officer of Isomorphic Labs, which was spun out of DeepMind. He discusses how AlphaFold 3's diffusion-based architecture enables unprecedented understanding of molecular interactions, and why we're approaching a "Move 37 moment" in AI-powered drug design where models will surpass human intuition. Max shares his vision for general AI models that can solve all diseases, and the importance of developing agents that can learn to search through the whole potential design space. Hosted by Stephanie Zhan, Sequoia Capital 00:00 - Introduction 02:33 - Key questions in RL 06:16 - Multiplayer games 11:05 - Finding the right recipe 13:13 - Working with Demis 15:47 - If everything goes right 21:44 - “A holy grail model” 26:08 - The breakthroughs of AlphaFold 35:00 - What kinds of data are missing? 37:34 - Limiting factors in drug development 40:00 - How do drug designers use AlphaFold 3? 43:46 - Building an interdisciplinary team 46:43 - AlphaFold Server 49:22 - The GPT-3 moment in AI biology 52:42 - When will we see the first AI-generated drug in clinic?
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