Wellbutrin (Bupropion) Works for ADHD

Dr. John Kruse October 3, 2024
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Dr. John Kruse

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Psychiatrist, neuroscientist, and author John Kruse, MD, PhD presents practical, actionable, well-researched information about treatment options that scientists and clinicians recommend for adult ADHD and other mental health conditions. Subscribe if you're curious about how neuroatypical brains can optimize their functioning in our shared, and somewhat strange, world. ADHD topics have a pink background, and those on more general mental health topics have a purple background. A small collection of Politics related videos have an orange background. Dr. Kruse has posted videos in the "Videos", "Live", and "Shorts", sections of this channel. You're welcome to email him with topics you want discussed or people you think he should interview. [email protected]

Video Description

Main chapters: 00:00 Intro - Wellbutrin and ADHD 00:11 Take home message 00:57 What is Wellbutrin 06:42 Wellbutrin side effects 09:50 Wellbutrin dosages 10:20 Deep dive 19:58 Clinical experience with Wellbutrin 20:54 Questions Clinicians have been using Wellbutrin to treat ADHD for at least three decades. Although the details still remain murky, Wellbutrin acts primarily as a norepinephrine and dopamine reuptake inhibitor. In humans, the norepinephrine effect appears to be more potent than the dopamine effect. Several studies, albeit with small numbers of patients, have shown Wellbutrin to be effective in reducing ADHD symptoms in children, adolescents, and adults. Wellbutrin helps at least as much as does Strattera (atomoxetine) and in several studies appears to be as effective as Ritalin (methylphenidate). Wellbutrin may be particularly attractive for those who want to avoid stimulant medications, and the potential for addiction. Confusion exists among most doctors, pharmacists and patients about the differences between the three formulations of bupropion (immediate release IR, sustained release SR, and extended release ER or XL). Although the XL form was approved for once a day dosing, this does NOT mean that medication is released steadily throughout a 24 hour period. ----- Free link to my Medium Article on Wellbutrin and ADHD: https://medium.com/wise-well/professionals-shouldnt-provide-medication-misinformation-373e64b5e5ef?sk=09ead0e464480ca46ee7d111e3146f5c Follow https://dockruse.medium.com on Medium for hundreds of full length articles on this subject and more! Access to other Medium articles requires paid membership. ----- References: Bupropion for attention deficit hyperactivity disorder (ADHD) in adults (2017) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485546/ Bupropion StatPearls https://www.ncbi.nlm.nih.gov/books/NBK470212/#:~:text=Bupropion%20has%20been%20FDA%2Dapproved,affective%20disorder%2C%20and%20smoking%20cessation. Correlating family nurse practitioners' perspectives of adult ADD/ADHD with employed pharmacotherapy: a pilot study (2010) https://pubmed.ncbi.nlm.nih.gov/20670268/ A comparison of the efficacy of medications for adult attention-deficit/hyperactivity disorder using meta-analysis of effect sizes. (2010) https://www.semanticscholar.org/paper/A-comparison-of-the-efficacy-of-medications-for-of-Faraone-Glatt/ea3f1ce2f1acd48c60b8cd305576b5fc81cc2862?p2df 15 Years of Clinical Experience With Bupropion HCl: From Bupropion to Bupropion SR to Bupropion XL (2005) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1163271/ Bupropion Hydrochloride in Attention Deficit Disorder with Hyperactivity (1996) https://www.sciencedirect.com/science/article/abs/pii/S0890856709636340 Full chapter list: 00:00 Intro - Wellbutrin and ADHD 00:11 Take home message 00:57 What is Wellbutrin 04:41 What does Wellbutrin do? 06:42 Wellbutrin side effects 09:50 Wellbutrin dosages 10:20 Deep dive 15:02 Wellbutrin Formulations 19:58 Clinical experience with Wellbutrin 20:54 Questions 21:09 How to know if Wellbutrin works on you 21:41 Wellbutrin and alcohol 22:20 Sunosi for ADHD 24:58 Alcohol and medication 25:37 Euphoria and Hypomania 26:16 Outro Streamed live on Sept 14, 2023 ------------------------- Psychiatrist, neuroscientist, and author John Kruse, MD, PhD presents practical, actionable, well-researched information about treatment options that scientists and clinicians recommend for adult ADHD and other mental health conditions. Subscribe if you're curious about how neuroatypical brains can optimize their functioning in our shared, and somewhat strange, world. ADHD topics have a pink background, and those on more general mental health topics have a purple background. A small collection of Politics related videos have an orange background. Dr. Kruse has posted videos in the "Videos", "Live", and "Shorts", sections of this channel. You're welcome to email him with topics you want discussed or people you think he should interview. [email protected] #health #mentalhealth #adhd #wellbutrin

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