Berberine: Overrated or Underrated? (Latest Research)

Leonid Kim MD October 6, 2025
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There is a lot of hype about this 'Miracle' Supplement, and there's claims it can help with diabetes, weight loss, cholesterol; some say it can slow down aging and even fight cancer? So in this video, I want talk about the actual science-backed evidence for using Berberine. Chapters 00:00 - Berberine Claims / Uses 00:49 - Blood Sugar Control / Diabetes 02:40 - Berberine Vs Metformin? 05:08 - Cholesterol 07:30 - Weight loss 09:45 - Cancer prevention 10:20 - Anti-aging 10:56 - My own approach 11:50 - Dihydroberberine (better absorption?) Dr Kim is a physician, board-certified in Internal and Obesity Medicine, with a passion for preventive health, weight loss, metabolic health, and longevity. Find me on: Instagram: http://www.instagram.com/leonidkimmd TikTok: http://www.tiktok.com/@leonidkimmd References: https://pubmed.ncbi.nlm.nih.gov/36467075/ https://pmc.ncbi.nlm.nih.gov/articles/PMC2909079/ https://www.ijbcp.com/index.php/ijbcp/article/view/6037 https://pmc.ncbi.nlm.nih.gov/articles/PMC5837225/figure/ehx144-F2/ https://pubmed.ncbi.nlm.nih.gov/36941490/ https://pubmed.ncbi.nlm.nih.gov/40740996/ https://pubmed.ncbi.nlm.nih.gov/33538260/ https://www.jacc.org/doi/10.1016/j.jacc.2018.11.003 https://pubmed.ncbi.nlm.nih.gov/40506769/ https://pmc.ncbi.nlm.nih.gov/articles/PMC12307485/ https://www.nejm.org/doi/full/10.1056/NEJMoa2032183 https://pubmed.ncbi.nlm.nih.gov/31926918/ https://www.nature.com/articles/srep12155 https://pubmed.ncbi.nlm.nih.gov/35010998/ DISCLAIMER: This video is for general information and educational purposes only and does NOT constitute the practice of medicine or other professional health services, including giving of a medical advice. NO doctor-patient relationship is formed. The use of this information and the materials provided in the video is at user’s own risk. The contents of the video are NOT intended to be a substitute for professional medical advice and are NOT intended to treat, diagnose, cure or prevent disease. You should NOT delay or disregard obtaining medical advice for any medical condition you have and you should first seek the assistance of your healthcare professional(s) for any such condition(s). You should NOT make any changes in your health regime, diet, medications, or supplements, before first consulting your physician or healthcare provider and before first obtaining a medical exam, diagnosis, and prescription/recommendation from your physician or healthcare provider. Leonid Kim MD will not assume any liability for any direct or indirect losses or damages that may result from use of the information contained in this video, including but not limited to, economic loss, injury, illness, or death. Furthermore, all content in the video is subject to change without notice, so the content creator assumes no responsibility for the accuracy of information contained. Please review all information regarding any medical condition or use of medications and/or supplements with your physician or healthcare provider. The contents of this video are my personal opinion and do not represent that of my employer(s).

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