Markus Buehler | Superintelligence for scientific discovery

Harvard CMSA September 24, 2025
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Big Data Conference 2025 9/11/2025 Speaker: Markus Buehler, MIT Title: Superintelligence for scientific discovery Abstract: AI is moving beyond prediction to become a partner in invention. While today’s models excel at interpolating within known data, true discovery requires stepping outside existing truths. This talk introduces superintelligent discovery engines built on multi-agent swarms: diverse AI agents that interact, compete, and cooperate to generate structured novelty. Guided by Gödel’s insight that no closed system is complete, these swarms create gradients of difference – much like temperature gradients in thermodynamics – that sustain flow, invention, and surprise. Case studies in protein design and music composition show how swarms escape data biases, invent novel structures, and weave long-range coherence, producing creativity that rivals human processes. By moving from “big data” to “big insight”, these systems point toward a new era of AI that composes knowledge across science, engineering, and the arts.

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