Morning Stiffness | Rheumatoid Arthritis | Osteoarthritis | Ankylosing Spondylitis, Septic Arthritis

Video Description

#podcast #drnajeeblectures #medicaleducation #drnajeeb #drnajeebpodcast Morning Stiffness | Rheumatoid Arthritis | Osteoarthritis | Ankylosing Spondylitis, Septic Arthritis Like this video? Sign up now on our website at https://www.DrNajeebLectures.com to access 1000+ Exclusive videos on Basic Medical Sciences & Clinical Medicine. These are premium videos (NOT FROM YOUTUBE). All these videos come with English subtitles & download options. Sign up now! Get Lifetime Access for a one-time payment of $16 ONLY! Sign up now on our website at https://members.drnajeeblectures.com/ ▬▬▬▬▬▬▬▬▬▬ Contents of this video ▬▬▬▬▬▬▬▬▬▬ 00:00:00 Introduction 00:00:12 Contents of the lecture 00:00:43 Clinical Conditions Associated with RA 00:01:15 Introduction to Morning Stiffness 00:01:45 First feature of Morning Stiffness 00:01:56 Second feature of Morning Stiffness 00:02:23 Third feature of Morning Stiffness 00:03:15 Gelling explanation and features 00:04:21 Differentiation between Morning Stiffness and Gelling 00:04:50 Hallmark of Inflammatory Arthritis 00:05:10 Clinical significance of Morning Stiffness 00:05:28 Constitutional features of Inflammatory Arthritis 00:06:29 Types of Inflammatory Arthritis 00:06:45 Osteoarthritis Pathophysiology 00:08:01 Inflammation in Osteoarthritis 00:08:36 Inflammatory Manifestations in RA 00:08:52 Significance of duration in RA 00:09:12 Scenario-based differentiation in the duration of Morning Stiffness in RA and osteoarthritis 00:10:21 The duration of morning stiffness in inflammatory arthritis is a key characteristic. 00:11:37 Relationship of duration and intensity of morning stiffness with underlying disease 00:12:17 Fluctuations in Morning Stiffness 00:12:40 Manifestations of Morning Stiffness 00:12:55 Joints involved in RA 00:13:35 Symptoms of Patients with Inflammatory Arthritis 00:14:38 Improvement of symptoms of Morning Stiffness by activity 00:15:06 Manifestations of patients of Poly Myalgia Rheumatica 00:17:21 Introduction to Rheumatoid Arthritis 00:18:35 Definition of Rheumatoid Arthritis 00:19:05 Explanation of clinical manifestations of RA 00:19:40 Alteration of proteins during RA 00:21:41Causes of genetic disposition in RA 00:22:51 Significance of citrullinated peptides 00:23:59 Immune-mediated injury of synovial joints 00:24:55 Difference between B cells and Plasma cells 00:25:55 Autoimmune response in RA 00:26:39 Cells accumulation at Synovial joints 00:27:47 Abnormal activation and proliferation of cells of Synovial joints 00:27:52 Synovial membrane cell types 00:29:33 Why does the synovial membrane not have an epithelial lining? 00:30:31 Process involved in immune system attack in RA 00:33:13 Important Chemical Mediators and Drugs Used Against Them 00:36:01 Introduction to DMARDs 00:36:46 MOA of DMARDs 00:39:22 Constituents of Pannus 00:40:38 Overview of RA 00:41:05 Presence of Synovial Membrane in various locations 00:41:42 Pathophysiology of Tenosynovitis 00:42:35 Non-suppurative Inflammation 00:43:25 Recap of the Definition of RA (Rheumatoid Arthritis) 00:44:20 Constituents of Pannus 00:46:08 Matrix Metalloproteinases and their roles 00:47:05 Pannus-induced pathological changes at synovial lining 00:48:11 Radiological features of RA explained 00:50:10 Diseases Associated with Marginal Erosions 00:50:50 Psoriatic arthritis clinical features 00:51:57 The key radiological feature of psoriatic arthritis. 00:53:30 Joints involved in Psoriatic arthritis 00:54:22 Difference between RA and Psoriatic Arthritis 00:57:39 Involvement of Distal Interphalangeal Joints in Inflammatory Arthritis 00:59:34 Recap of RA 01:00:58 Difference between Arthralgia and Arthritis 01:01:57 Constitutional features of RA 01:02:18 Malaise definition 01:02:38 Alteration of the function of the Hypothalamus by Cytokines 01:04:28 Extra-articular complications in RA patients 01:07:17 Steps involved in extra-articular complications of RA 01:08:25 Type III Hypersensitivity Pathophysiology 01:09:00 Constitutional and Articular features of RA 01:09:54 Underlying mechanism of swollen joints in RA and osteoarthritis 01:11:11 Radiological Differentiation Between Rheumatoid Arthritis and Osteoarthritis 01:13:14 Heberden’s Node in Distal Interphalangeal joints 01:14:51 Differential clinical features of RA and Osteoarthritis 01:15:43 Radiological differentiation between RA and Osteoarthritis 01:20:45 Age-related difference between RA and Osteoarthritis 01:21:13 Differentiating Rheumatoid Arthritis (RA) from Osteoarthritis based on constitutional features. 01:23:00 Overview of lecture 01:24:19 Ankylosing Spondylitis and its Clinical Features 01:27:51 A quick recap of all the conditions associated with morning stiffness. 01:29:47 Brief review. 01:32:07 Q&A session. 01:33:05 Overview of next lecture. 01:34:08 End of lecture.