A Masterclass on Cardiovascular Risk: Decoding Lipoprotein(a) | Dr Dayspring | The Proof EP #320

Video Description

Are you part of the 20% of people with this dangerous gene? There’s a cheap, simple test you can do just once in your life to find out. Join me in Episode #320 as I sit down with renowned lipidologist Dr Thomas Dayspring to help you understand Lipoprotein(a) and the test that might change your life. Specifically, we discuss: 00:00 - Introduction 00:13 - Demystifying Lipoprotein(a): An Overview of its Role in Cardiovascular Health 06:32 - Genetic Inheritance Patterns and Variability of Lipoprotein(a) 11:11 - Drug Development Strategies for Reducing Lipoprotein(a) Levels 16:49 - Exploring the Functional Role and Genetic Variations of Lipoprotein(a) 28:57 - Inside the Artery Walls: Mechanisms and Structure of Lipoprotein(a) 38:54 - A Deep Dive in Production to Measurement of Lipoprotein(a) 56:21 - Identifying High-Risk Indicators for Lipoprotein(a) 01:09:07 - Statins and Elevated Lipoprotein(a): Understanding the Relationship 01:17:53 - Exploring PCSK9 Inhibitors in Lipoprotein(a) Management 01:28:48 - Emerging Treatments and Future Therapies for Lowering Lipoprotein(a) 01:32:06 - Exploring Lifestyle Considerations and Alternative Therapies 01:40:41 - Oxidized Phospholipids and Their Role in Cardiovascular Health 01:49:25 - Relationship Between Oxidized Phospholipids and Lipoprotein(a) 01:57:06 - Understanding Aortic Valve Calcification and Its Link to Lipoprotein(a) 02:04:17 - Key Takeaways and Future Landscape of Lipoprotein(a) Treatments 02:10:57 - Conclusion and Final Remarks 👇 Visit The Proof website for the full show notes and supporting studies. 👇 https://theproof.com/podcast/ Dr Thomas Dayspring is a Fellow of both the American College of Physicians and the National Lipid Association and is certified in internal medicine and clinical lipidology. He is currently a virtual cardiovascular educational research assistant and clinical lipidologist at a prestigious national practice and has given over 4000 domestic and international lectures among many other notable achievements. As we saw in the Dr Dayspring’s lipid series on The Proof, he is adept at communicating complex science in an accessible way and brings this skill to today’s episode. Connect with Dr Thomas Dayspring: - Twitter/X: https://twitter.com/Drlipid - Previous lipid series and cheat sheet: https://theproof.com/lipid-series/ If you have any additional questions you would like answered in the future, let me know in the comments. The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. Enjoy, friends. Simon This episode is brought to you by: 38TERA Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Head to https://38tera.com and use code THEPROOF for a discount at checkout. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on http://join.whoop.com/simon Cozy Earth Sleep better and cooler with Cozy Earth, the softest science-backed sheets on the market. With a 10-year warranty, 100-day trial period, and ethical production, Cozy Earth is my favourite easy way to improve my rest and recovery. Use code SIMON at http://cozyearth.com/ for up to 35% off. BON CHARGE Enhance skin health, increase collagen production, and reverse sun damage with BON CHARGE, my choice of low-level light therapy. Holistic, evidence-based, premium products for healthier skin. Get started at http://boncharge.com/ and use code THEPROOF for a 15% discount. Simon Hill, MSc, BSc (Hons) Creator of http://theproof.com/ and host of https://theproof.com/podcast/ Author of https://theproof.com/book/ Watch the episodes on YouTube https://www.youtube.com/c/TheProofWithSimonHill/videos or listen on Apple https://podcasts.apple.com/au/podcast/the-proof-with-simon-hill/id1367773989 / Spotify https://open.spotify.com/show/7bAIJCVgnquxXZuQCdZyTi?si=84831dc34dc9408b Connect with me on https://www.instagram.com/theproof/, https://mobile.twitter.com/theproof, and https://facebook.com/theproofwithsimonhill Nourish your gut with my Plant-Based Ferments Guide https://theproof.com/ferments/ Download my complimentary Two-Week Meal Plan https://plantproof.com/mealplan and high protein Plant Performance recipe book https://theproof.com/performance/