The Science of Neurogenesis, Psilocybin & The Stamets Stack | Paul Stamets

Mark Hyman, MD September 6, 2023
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Explore the hidden blueprints of Earth's natural internet and the evolutionary foundations of our survival. This discussion explores the profound potential of psilocybin for the prevention of mental illness and PTSD, highlighting the interconnected network of fungus that runs our world. This conversation explores why the often-neglected world of fungi is essential to both planetary well-being and human health. From creating the very soil that sustains our agriculture to offering complex immune system support, mushrooms act as a vital bridge between ancient indigenous wisdom and modern clinical healing. Paul Stamets and Dr. Mark Hyman examine why these psychedelics have been historically neglected, despite their significance in neuroscience and healing. Understanding the importance of mycology is crucial for addressing mental health challenges and breaking the cycle of trauma and chronic inflammation. The discussion dives deep into the neurobiology of psilocybin, explaining how it substitutes for serotonin and docks with TRKB receptors to stimulate Brain-Derived Neurotrophic Factor (BDNF), essentially acting as "miracle grow" for the brain. Stamets details the "Stamets Stack"—a microdosing protocol combining psilocybin, Lion’s Mane, and niacin designed to enhance neuroplasticity and improve psychomotor skills in aging populations. Beyond individual wellness, they envision a future where these "peace molecules" foster collaborative communities and shift societal paradigms toward a shared, giant consciousness Learn more at https://paulstamets.com. Get my FREE guide 3 Steps to Reverse Aging when you sign up for my weekly health picks 👉 https://bit.ly/IncreaseHealthspan This episode is brought to you by Rupa Health, Sensate, ButcherBox, and Thrive Market. Access more than 3,000 specialty lab tests with Rupa Health. You can check out a free, live demo with a Q&A or create an account at https://RupaHealth.com today. Head on over to https://getsensate.com/Farmacy and use code FARMACY to get 10% off your Sensate device today. For new members of ButcherBox, you can receive New York strip steaks for a year PLUS $20 off your first order. Go to https://ButcherBox.com/farmacy and use code FARMACY. Thrive Market is offering 30% off your first order and a free gift of up to $60 if you sign up now! Head over to https://thrivemarket.com/Hyman today. (0:00) Introduction to the potential of sulcivulin for mental illness prevention (0:06) Importance and role of fungi in the ecosystem and their evolutionary significance (1:02) The birth of animals from fungi and the impact on plant health (5:37) Unexplored mycelial networks in oceans and their benefits (6:55) Nutritional and medicinal benefits of mushrooms, including psilocybin (11:11) Mycelium's role in ecological communities and mental health (25:40) Continued discussion on psilocybin's impact and research (33:13) Historical and indigenous use of psilocybin; future applications (46:39) Psilocybin's societal benefits and conservative support for legalization (51:05) Sponsor: [Sponsor Name] (51:53) Approaches to change and the debate on microdosing vs. macrodosing (54:17) Research on neurodegenerative disorders and psychomotor benefits (59:04) Mechanism of action, neurogenesis, and development of clinical studies (1:03:20) Microdosing impact on various conditions and future projections (1:07:05) Psilocybin's role in addressing the obesity epidemic (1:11:25) Paul Stamets' daily routine and final thoughts on psilocybin mushrooms (1:17:24) The unity of consciousness and outro remarks by Dr. Hyman (1:17:41) The role of genes in health and environmental influences (1:19:05) Practical steps to influence your genes (1:20:02) Sponsor message from Thorne (1:20:45) The future of personalized medicine #PaulStamets #MarkHyman #Psilocybin #Mycology #Neurogenesis #MentalHealth #PTSD #Microdosing #BrainHealth #StametsStack #Mycelium #Neuroscience #Healing #MushroomScience

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