Why Your Microbiome Could Be Raising Your Uric Acid

Dr. Michael Ruscio, DC, DNM March 31, 2025
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Dr. Michael Ruscio, DC, DNM

@drrusciodc

About

Dr. Ruscio Radio is hosted by Dr. Michael Ruscio, DC, DNM, a functional medicine clinician and researcher specializing in gut health, autoimmune disease, thyroid disorders, and chronic illness. This channel breaks down functional medicine research into clear, practical steps to help you heal—without the bias and the noise. Rooted in published clinical research, our work focuses on the gut as the foundation of health and its impact on immunity, hormones, and brain function. Topics include: - Gut health: SIBO, IBS, GERD, candida & parasites - Autoimmune & thyroid conditions (Hashimoto’s, Graves’) - Histamine intolerance, mast cell activation & immune health - Lyme, mold illness & chronic infections - Brain-gut health: brain fog, anxiety, depression & insomnia If you want science-backed functional medicine guidance you can trust, you’re in the right place.

Video Description

I’m excited to have Dr. David Perlmutter back on the podcast to discuss uric acid and its pivotal connection to our overall health. Which foods lower and raise uric acid? What is its role in diabetes, alzheimer’s, gut health, and brain health? All of this will be covered, as well as best protocols for lowering high uric acid. You don’t want to miss this! Listen now! Learn more about lowering uric acid in Dr. Perlmutter’s book, Drop Acid! https://drperlmutter.com/learn/books/ Connect with Dr. Perlmutter online: https://www.instagram.com/davidperlmutter/ www.drperlmutter.com Need help navigating your digestive or other health conditions? Learn more about our virtual clinic: https://drruscio.com/virtual-clinic/ 👇 Watch more videos like this 👇 ➡️The Power of Probiotics: Regulate Glucose Levels: https://www.youtube.com/watch?v=zx7sUKWNs6M ➡️Health Science Snapshot NEW Healthy Lifestyle Research July 2023: https://www.youtube.com/watch?v=BGCJhMM7Tdk ➡️Berberine Benefits: Which Are Real and Which Are Hype?: https://www.youtube.com/watch?v=uyJQSDY0gRc ➡️Top Nutrient Dense Foods You Should Be Eating With Dr. Sarah Ballantyne: https://www.youtube.com/watch?v=76i5lWM8kNo Subscribe: https://www.youtube.com/@DrRuscioDC?sub_confirmation=1 And if you have any questions or topics you would like covered in the future, let me know in the comments! 👇Read these next 👇 ➡️ How to Heal Your Gut Naturally: A Clinician’s Guide https://drruscio.com/how-to-heal-your-gut-naturally/ ➡️ Beyond Diet: What Causes Blood Sugar Spikes? https://drruscio.com/blood-sugar-spikes/ ➡️ 8 Best Microbiome Supplements for a Happier, Healthier Gut https://drruscio.com/best-microbiome-supplements/ Timestamps 00:00 Intro 01:30 Why uric acid is pivotal to health 05:57 Evolutionary origins of high uric acid 07:12 Why fructose is a major factor 13:10 What elevates uric acid? 18:47 How to monitor levels 24:22 Foods that raise vs. lower UA 25:43 Relation to diabetes & other diseases 29:40 Probiotic protocol to lower UA 31:39 Connection to gut health 35:59 Connection to brain health 44:10 New therapeutics to explore 52:49 How to lower uric acid 57:37 Final takeaways Featured Studies 📉Safety and efficacy of probiotic supplementation in 8 types of inflammatory arthritis: https://pubmed.ncbi.nlm.nih.gov/36217542/ 📉Could Alzheimer's disease be a maladaptation of an evolutionary survival pathway mediated by intracerebral fructose and uric acid metabolism?: https://pubmed.ncbi.nlm.nih.gov/36774227/ Follow Me Facebook - https://www.facebook.com/DrRuscio Instagram - https://www.instagram.com/drruscio/ TikTok - https://www.tiktok.com/@drrusciodc DISCLAIMER: The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider before starting any new treatment or discontinuing an existing treatment. Music featured in this video: "Modern Technology" by Andrew G, https://audiojungle.net/user/andrew_g *Full transcript available on YouTube by clicking the “Show transcript” button on the bottom right of the video.

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